PMMH’s weekly seminar is held every Friday at 11 am (map)
Alice Pelosse
Stéphane Perrard
Etienne Reyssat
Virgile Thiévenaz
PMMH
BARRE CASSAN
BAT A 1ER ETAGE CASE 18
7 QUAI SAINT BERNARD
75005 PARIS
France
Tel : (33) 1 40 79 45 22
Séminaire PMMH – Nicolas Roméo (James Franck Institute, Chicago)
Canalizing biological self-organization with physical constraints
Modern imaging and genetic engineering allow for unprecedented access into the dynamics of biological self-organization, yet understanding how spatial organization emerges robustly remains challenging in these noisy, nonlinear living systems. I will present experimental and theoretical results highlighting how (long-range) physical constraints can explain the stability of emergent patterns.
On the experimental front, we study the emergence of chiral symmetry breaking in the coiling of the embryonic fly midgut, which displays a remarkable bistability in outcome under molecular perturbations. Using whole-organ live imaging, covariant measures of tissue dynamics, and mechanical modeling, we outline a ‘mechanical Waddington landscape' framework to explain the global stability of chiral organ morphogenesis.
On the theoretical front, by viewing self-organization as noisy encoding, we prove that the positional information capacity of short-range classical systems with discrete states is fundamentally limited, and show how this limit can be bypassed when long-range correlations are present. Together, these results show how biological and physical processes can cooperate to enable and regulate developmental process.
- Seminar archive
- Recent seminars
- Seminars
Seminars (2)
-
Séminaire PMMH – Gautier Verhille (IRPHÉ)
Vendredi 10 avril de 11h00 à 12h00 - Salle réunion PMMH 1
Formation and fragmentation of fiber aggregate in turbulent flows
Fiber aggregates are commonly encountered in environmental and industrial flows (paper industry, fiber recycling, etc.). However, the physical mechanisms leading to their formation are still misunderstood. Hence, there is still no clear answer to simple questions such as : how long will it take for an aggregate to (…) -
Séminaire PMMH – Pas de séminaire
Vendredi 24 avril de 11h00 à 12h00 - Salle réunion PMMH 1
The audience is composed of people with rather heterogeneous backgrounds including specialists in solids, fluids, granular flows, statistical physics... so the idea is to keep your talk understandable by people not necessarily working in your field... The seminar time slot runs from 11am to noon so the best is to make the talk last around 45 minutes to leave some time for discussion.
- Séminaires ESPCI-ENS de biophysique
- Séminaires du Département de Physique de l’ENS
- Séminaires du Laboratoire d’Hydrodynamique de l’X
- Séminaire de Mécanique d’Orsay (page web FAST)
- Séminaire de Mécanique d’Orsay (page web LIMSI)
- Séminaire de Mécanique des Fluides de l’Institut Jean le Rond d’Alembert
- Séminaires du laboratoire MSC, Paris VII
- Séminaires Gulliver
br >
br >


